Pathologic response prediction and neoadjuvant rectal score evaluation in patients with rectal cancer
نویسندگان
چکیده
منابع مشابه
Comparison of 5FU-base Chemoradiation with and without Eloxatin on Pathologic Complete Response in Neoadjuvant Chemoradiation of Rectal cancer
Background and Objectives: To compare pathologic complete response (pCR) in patients with advanced rectal cancer receiving neoadjuvant chemoradiotherapy (NACT) by 5-FU or Xeloda (capecitabine) with and without Eloxatin (oxaloplatin injection). Materials and Methods: Seventy-five consecutive patients with the diagnosis of advanced rectal adenocarcinoma were included. Two basic chemotherapy r...
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Background: Colorectal carcinoma is the third most common cause of death in Iran. This study was performed in order to determine the appropriate distal clearance margin (DCM) for resection of rectal cancer in patients who undergo neoadjuvant chemoradiotherapy for sphincter preserving procedure. Materials and Methods: This was a cross-sectional study conducted in Shahid Faghihi Hospital of Shira...
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Background: In recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. In this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...
متن کاملcomparison of 5fu-base chemoradiation with and without eloxatin on pathologic complete response in neoadjuvant chemoradiation of rectal cancer
background and objectives: to compare pathologic complete response (pcr) in patients with advanced rectal cancer receiving neoadjuvant chemoradiotherapy (nact) by 5-fu or xeloda (capecitabine) with and without eloxatin (oxaloplatin injection). materials and methods: seventy-five consecutive patients with the diagnosis of advanced rectal adenocarcinoma were included. two basic chemotherapy regi...
متن کاملNeoadjuvant Rectal (NAR) Score: a New Surrogate Endpoint in Rectal Cancer Clinical Trials
The conduct of clinical trials in colorectal cancer has historically relied upon endpoints such as disease-free (DFS) or overall survival (OS). While ideal, these endpoints require long-term follow-up, thus contributing to a slow pace of scientific progress in clinical research. Identification of short-term endpoints to serve as surrogates for DFS and OS would enable more rapid determination of...
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ژورنال
عنوان ژورنال: The Annals of Clinical and Analytical Medicine
سال: 2019
ISSN: 2667-663X
DOI: 10.4328/acam.6047